Global pharmaceutical industry by wages and salaries per employee 2006-2014 Outsourced research penetration in pharmaceutical industry worldwide 2011-2020 Global pharmaceutical industry by production value 2006-2018Ĭhanges in forward P/E ratios in the pharmaceutical industry 2015-2016 Total number of pharma and biotech merger and acquisition deals 2015-2022 Number of biopharma venture financing deals 2017-2022 This makes cooperation with technology companies necessary and includes data gathered from various sources, even that of social media. Particularly, real-time or real-world evidence (RWE) is becoming a greater interest. Thus, a predictive modeling is possible which uses clinical and molecular data to develop safer and more efficient drugs. Another important development is the use of big data in clinical research. A growing number of drug manufacturers are outsourcing large parts of R&D, mostly to clinical research organizations (also contract research organizations), with the main aim to reduce costs. ![]() Two major effects of patent expirations for the pharma industry are a specific high R&D intensity and a growing focus on specialty drugs to diversify their product portfolio.įor the last several years, major developments in pharmaceutical research and development have begun to change the R&D landscape. This is largely due to the time-limited patent protection of drugs and the following threat of sales erosion through generic and biosimilar competition. In comparison to other industries, pharmaceutical companies are more driven by the imperative to manufacture innovative products, and thus to spend significant amounts on research and development. ![]() In the United States, the Food and Drug Administration is the principal agency associated with processes. At a certain point in the process – mostly during the pre-clinical phase – a governmental authority is involved to overview, regulate, and ultimately approve the drug. Pharmaceutical R&D includes all steps from the initial research of disease processes, the compound testing over pre-clinical, and all clinical trial stages. For comparison, R&D expenditures totaled 137 billion dollars in 2012. In 2021, research and development spending in the pharmaceutical industry totaled some 238 billion U.S.
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